Endocrine Abstracts

Background: Fibroblast growth factor 21 (FGF21) is a hormone induced in the liver by metabolic stressors including starvation, sugars, and ethanol. Alcohol consumption increases endogenous FGF21 levels in humans while administration of FGF21 has been shown to reduce alcohol consumption in non-human primates. The effect of acute moderate alcohol consumption and long-term alcohol cessation on FGF21 levels in humans is controversial. We hypothesize that even moderate alcohol cons...

Background: Patients with acromegaly without detectable pituitary adenoma on conventional MRI are often excluded from adenomectomy due to inherent challenges of precise surgical planning, significantly limiting both their therapeutic options and chances of curation. Previous research showed that O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) PET-MRI is an accurate diagnostic tool to detect small functional pituitary adenomas (1). The present study aims to investigate the diagnos...